diff --git a/src/portable/raspberrypi/rp2040/hcd_rp2040.c b/src/portable/raspberrypi/rp2040/hcd_rp2040.c
index 661255cf6..02f9968a7 100644
--- a/src/portable/raspberrypi/rp2040/hcd_rp2040.c
+++ b/src/portable/raspberrypi/rp2040/hcd_rp2040.c
@@ -562,6 +562,11 @@ bool hcd_edpt_xfer(uint8_t rhport, uint8_t dev_addr, uint8_t ep_addr, uint8_t *
     uint32_t flags = USB_SIE_CTRL_START_TRANS_BITS | SIE_CTRL_BASE |
                      (ep_dir ? USB_SIE_CTRL_RECEIVE_DATA_BITS : USB_SIE_CTRL_SEND_DATA_BITS) |
                      (need_pre(dev_addr) ? USB_SIE_CTRL_PREAMBLE_EN_BITS : 0);
+    // START_TRANS bit on SIE_CTRL seems to exhibit the same behavior as the AVAILABLE bit
+    // described in RP2040 Datasheet, release 2.1, section "4.1.2.5.1. Concurrent access".
+    // We write everything except the START_TRANS bit first, then wait some cycles.
+    usb_hw->sie_ctrl = flags & ~USB_SIE_CTRL_START_TRANS_BITS;
+    busy_wait_at_least_cycles(12);
     usb_hw->sie_ctrl = flags;
   }else
   {
@@ -602,6 +607,11 @@ bool hcd_setup_send(uint8_t rhport, uint8_t dev_addr, uint8_t const setup_packet
   uint32_t const flags = SIE_CTRL_BASE | USB_SIE_CTRL_SEND_SETUP_BITS | USB_SIE_CTRL_START_TRANS_BITS |
                          (need_pre(dev_addr) ? USB_SIE_CTRL_PREAMBLE_EN_BITS : 0);
 
+  // START_TRANS bit on SIE_CTRL seems to exhibit the same behavior as the AVAILABLE bit
+  // described in RP2040 Datasheet, release 2.1, section "4.1.2.5.1. Concurrent access".
+  // We write everything except the START_TRANS bit first, then wait some cycles.
+  usb_hw->sie_ctrl = flags & ~USB_SIE_CTRL_START_TRANS_BITS;
+  busy_wait_at_least_cycles(12);
   usb_hw->sie_ctrl = flags;
 
   return true;