diff --git a/rpcs3/rpcs3qt/gs_frame.cpp b/rpcs3/rpcs3qt/gs_frame.cpp
index df3d55d8a9..afd1de3ccc 100644
--- a/rpcs3/rpcs3qt/gs_frame.cpp
+++ b/rpcs3/rpcs3qt/gs_frame.cpp
@@ -39,8 +39,28 @@ void gs_frame::keyPressEvent(QKeyEvent *keyEvent)
 	{
 		switch (keyEvent->key())
 		{
-		case Qt::Key_Return: if (keyEvent->modifiers() == Qt::AltModifier) { OnFullScreen(); return; } break;
-		case Qt::Key_Escape: if (visibility() == FullScreen) { setVisibility(Windowed); return; } break;
+		case Qt::Key_Return:
+			if (keyEvent->modifiers() == Qt::AltModifier) { OnFullScreen(); return; }
+			break;
+		case Qt::Key_Escape:
+			if (visibility() == FullScreen) { setVisibility(Windowed); return; }
+			break;
+		case Qt::Key_P:
+			if (keyEvent->modifiers() == Qt::ControlModifier && Emu.IsRunning()) { Emu.Pause(); return; }
+			break;
+		case Qt::Key_S:
+			if (keyEvent->modifiers() == Qt::ControlModifier && (!Emu.IsStopped())) { Emu.Stop(); return; }
+			break;
+		case Qt::Key_R:
+			if (keyEvent->modifiers() == Qt::ControlModifier && (!Emu.GetPath().empty())) { Emu.Stop(); Emu.Load(); return; }
+			break;
+		case Qt::Key_E:
+			if (keyEvent->modifiers() == Qt::ControlModifier)
+			{
+				if (Emu.IsReady()) { Emu.Run(); return; }
+				else if (Emu.IsPaused()) { Emu.Resume(); return; }
+			}
+			break;
 		}
 	};
 	Emu.CallAfter(l_handleKeyEvent);
diff --git a/rpcs3/rpcs3qt/main_window.cpp b/rpcs3/rpcs3qt/main_window.cpp
index 792d5da31a..caa7604c9f 100644
--- a/rpcs3/rpcs3qt/main_window.cpp
+++ b/rpcs3/rpcs3qt/main_window.cpp
@@ -787,7 +787,6 @@ void main_window::CreateActions()
 	sysPauseAct->setIcon(icon_pause);
 
 	sysStopAct = new QAction(tr("&Stop"), this);
-	sysStopAct->setShortcut(tr("Ctrl+S"));
 	sysStopAct->setEnabled(false);
 	sysStopAct->setIcon(icon_stop);
 
@@ -1166,12 +1165,15 @@ void main_window::ConfigureGuiFromSettings(bool configureAll)
 
 void main_window::keyPressEvent(QKeyEvent *keyEvent)
 {
-	switch (keyEvent->key())
+	if (keyEvent->modifiers() == Qt::ControlModifier)
 	{
-	case 'E': case 'e': if (Emu.IsPaused()) Emu.Resume(); else if (Emu.IsReady()) Emu.Run(); return;
-	case 'P': case 'p': if (Emu.IsRunning()) Emu.Pause(); return;
-	case 'S': case 's': if (!Emu.IsStopped()) Emu.Stop(); return;
-	case 'R': case 'r': if (!Emu.GetPath().empty()) { Emu.Stop(); Emu.Run(); } return;
+		switch (keyEvent->key())
+		{
+		case Qt::Key_E: if (Emu.IsPaused()) Emu.Resume(); else if (Emu.IsReady()) Emu.Run(); return;
+		case Qt::Key_P: if (Emu.IsRunning()) Emu.Pause(); return;
+		case Qt::Key_S: if (!Emu.IsStopped()) Emu.Stop(); return;
+		case Qt::Key_R: if (!Emu.GetPath().empty()) { Emu.Stop(); Emu.Run(); } return;
+		}
 	}
 }