diff --git a/configs/crypto-config-ccm-psk-tls1_2.h b/configs/crypto-config-ccm-psk-tls1_2.h
index 561324aa58..e4de8b3fb6 100644
--- a/configs/crypto-config-ccm-psk-tls1_2.h
+++ b/configs/crypto-config-ccm-psk-tls1_2.h
@@ -24,7 +24,6 @@
 #define PSA_WANT_KEY_TYPE_AES                   1
 
 #define MBEDTLS_PSA_CRYPTO_C
-#define MBEDTLS_USE_PSA_CRYPTO
 
 /* System support */
 //#define MBEDTLS_HAVE_TIME /* Optionally used in Hello messages */
diff --git a/configs/crypto-config-suite-b.h b/configs/crypto-config-suite-b.h
index dcb814562d..3eea061262 100644
--- a/configs/crypto-config-suite-b.h
+++ b/configs/crypto-config-suite-b.h
@@ -40,7 +40,6 @@
 #define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_GENERATE  1
 
 #define MBEDTLS_PSA_CRYPTO_C
-#define MBEDTLS_USE_PSA_CRYPTO
 
 /* System support */
 #define MBEDTLS_HAVE_ASM
diff --git a/configs/crypto-config-symmetric-only.h b/configs/crypto-config-symmetric-only.h
index 5393541625..dfe9e81251 100644
--- a/configs/crypto-config-symmetric-only.h
+++ b/configs/crypto-config-symmetric-only.h
@@ -58,7 +58,6 @@
 #define MBEDTLS_SELF_TEST
 
 #define MBEDTLS_PSA_CRYPTO_C
-#define MBEDTLS_USE_PSA_CRYPTO
 
 /* System support */
 //#define MBEDTLS_HAVE_ASM
diff --git a/configs/crypto-config-thread.h b/configs/crypto-config-thread.h
index a17ae5dc8f..f71b1f079a 100644
--- a/configs/crypto-config-thread.h
+++ b/configs/crypto-config-thread.h
@@ -45,7 +45,6 @@
 #define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_GENERATE 1
 
 #define MBEDTLS_PSA_CRYPTO_C
-#define MBEDTLS_USE_PSA_CRYPTO
 
 /* System support */
 #define MBEDTLS_HAVE_ASM