diff --git a/tests/include/test/psa_crypto_helpers.h b/tests/include/test/psa_crypto_helpers.h
index ac6eb2083a..f27f88eb6b 100644
--- a/tests/include/test/psa_crypto_helpers.h
+++ b/tests/include/test/psa_crypto_helpers.h
@@ -295,6 +295,7 @@ int mbedtls_test_fail_if_psa_leaking(int line_no, const char *filename);
 #define PSA_INIT_IF_NO_MD() ((void) 0)
 #define PSA_DONE_IF_NO_MD() ((void) 0)
 #endif
+
 /** \def USE_PSA_INIT
  *
  * Call this macro to initialize the PSA subsystem if #MBEDTLS_USE_PSA_CRYPTO
@@ -321,4 +322,9 @@ int mbedtls_test_fail_if_psa_leaking(int line_no, const char *filename);
 #define USE_PSA_DONE() ((void) 0)
 #endif /* !MBEDTLS_USE_PSA_CRYPTO && !MBEDTLS_SSL_PROTO_TLS1_3 */
 
+#if !defined(MBEDTLS_PSA_CRYPTO_C)
+#define PSA_INIT() ((void) 0)
+#define PSA_DONE() ((void) 0)
+#endif /* MBEDTLS_PSA_CRYPTO_C */
+
 #endif /* PSA_CRYPTO_HELPERS_H */