diff --git a/src/core/tcp.c b/src/core/tcp.c
index 8712d76c..f72597bb 100644
--- a/src/core/tcp.c
+++ b/src/core/tcp.c
@@ -880,10 +880,11 @@ tcp_connect(struct tcp_pcb *pcb, const ip_addr_t *ipaddr, u16_t port,
 #endif /* SO_REUSE */
   }
 
-  iss = tcp_next_iss();
+  iss = tcp_next_iss(pcb);
   pcb->rcv_nxt = 0;
   pcb->snd_nxt = iss;
   pcb->lastack = iss - 1;
+  pcb->snd_wl2 = iss - 1;
   pcb->snd_lbb = iss - 1;
   /* Start with a window that does not need scaling. When window scaling is
      enabled and used, the window is enlarged when both sides agree on scaling. */
@@ -1491,7 +1492,6 @@ struct tcp_pcb *
 tcp_alloc(u8_t prio)
 {
   struct tcp_pcb *pcb;
-  u32_t iss;
 
   pcb = (struct tcp_pcb *)memp_malloc(MEMP_TCP_PCB);
   if (pcb == NULL) {
@@ -1554,11 +1554,6 @@ tcp_alloc(u8_t prio)
     pcb->sv = 3000 / TCP_SLOW_INTERVAL;
     pcb->rtime = -1;
     pcb->cwnd = 1;
-    iss = tcp_next_iss();
-    pcb->snd_wl2 = iss;
-    pcb->snd_nxt = iss;
-    pcb->lastack = iss;
-    pcb->snd_lbb = iss;
     pcb->tmr = tcp_ticks;
     pcb->last_timer = tcp_timer_ctr;
 
@@ -1826,12 +1821,18 @@ tcp_pcb_remove(struct tcp_pcb **pcblist, struct tcp_pcb *pcb)
  * @return u32_t pseudo random sequence number
  */
 u32_t
-tcp_next_iss(void)
+tcp_next_iss(struct tcp_pcb *pcb)
 {
+#ifdef LWIP_HOOK_TCP_ISN
+  return LWIP_HOOK_TCP_ISN(&pcb->local_ip, pcb->local_port, &pcb->remote_ip, pcb->remote_port);
+#else /* LWIP_HOOK_TCP_ISN */
   static u32_t iss = 6510;
 
+  LWIP_UNUSED_ARG(pcb);
+
   iss += tcp_ticks;       /* XXX */
   return iss;
+#endif /* LWIP_HOOK_TCP_ISN */
 }
 
 #if TCP_CALCULATE_EFF_SEND_MSS
diff --git a/src/core/tcp_in.c b/src/core/tcp_in.c
index 7f42f577..3d3ae33a 100644
--- a/src/core/tcp_in.c
+++ b/src/core/tcp_in.c
@@ -542,6 +542,7 @@ static void
 tcp_listen_input(struct tcp_pcb_listen *pcb)
 {
   struct tcp_pcb *npcb;
+  u32_t iss;
   err_t rc;
 
   if (flags & TCP_RST) {
@@ -589,6 +590,11 @@ tcp_listen_input(struct tcp_pcb_listen *pcb)
     npcb->state = SYN_RCVD;
     npcb->rcv_nxt = seqno + 1;
     npcb->rcv_ann_right_edge = npcb->rcv_nxt;
+    iss = tcp_next_iss(npcb);
+    npcb->snd_wl2 = iss;
+    npcb->snd_nxt = iss;
+    npcb->lastack = iss;
+    npcb->snd_lbb = iss;
     npcb->snd_wl1 = seqno - 1;/* initialise to seqno-1 to force window update */
     npcb->callback_arg = pcb->callback_arg;
 #if LWIP_CALLBACK_API || TCP_LISTEN_BACKLOG
diff --git a/src/include/lwip/ip_addr.h b/src/include/lwip/ip_addr.h
index bce65edd..def2d08c 100644
--- a/src/include/lwip/ip_addr.h
+++ b/src/include/lwip/ip_addr.h
@@ -66,7 +66,7 @@ enum lwip_ip_addr_type {
  * A union struct for both IP version's addresses.
  * ATTENTION: watch out for its size when adding IPv6 address scope!
  */
-typedef struct _ip_addr {
+typedef struct ip_addr {
   union {
     ip6_addr_t ip6;
     ip4_addr_t ip4;
diff --git a/src/include/lwip/opt.h b/src/include/lwip/opt.h
index d350f3ce..98180c62 100644
--- a/src/include/lwip/opt.h
+++ b/src/include/lwip/opt.h
@@ -2410,6 +2410,29 @@
  * @{
  */
 
+/**
+ * LWIP_HOOK_TCP_ISN:
+ * Hook for generation of the Initial Sequence Number (ISN) for a new TCP
+ * connection. The default lwIP ISN generation algorithm is very basic and may
+ * allow for TCP spoofing attacks. This hook provides the means to implement
+ * the standardized ISN generation algorithm from RFC 6528, or any other
+ * desired algorithm (e.g., it can be set to LWIP_RAND()), as a replacement.
+ * Called from tcp_connect() and tcp_listen_input() when an ISN is needed for
+ * a new TCP connection, if TCP support (@ref LWIP_TCP) is enabled.\n
+ * Signature: u32_t my_hook_tcp_isn(const ip_addr_t* local_ip, u16_t local_port, const ip_addr_t* remote_ip, u16_t remote_port);
+ * - it may be necessary to use "struct ip_addr" (ip4_addr, ip6_addr) instead of "ip_addr_t" in function declarations\n
+ * Arguments:
+ * - local_ip: pointer to the local IP address of the connection
+ * - local_port: local port number of the connection (host-byte order)
+ * - remote_ip: pointer to the remote IP address of the connection
+ * - remote_port: remote port number of the connection (host-byte order)\n
+ * Return value:
+ * - the 32-bit Initial Sequence Number to use for the new TCP connection.
+ */
+#ifdef __DOXYGEN__
+#define LWIP_HOOK_TCP_ISN(local_ip, local_port, remote_ip, remote_port)
+#endif
+
 /**
  * LWIP_HOOK_IP4_INPUT(pbuf, input_netif):
  * - called from ip_input() (IPv4)
diff --git a/src/include/lwip/priv/tcp_priv.h b/src/include/lwip/priv/tcp_priv.h
index f0eeb450..f68a856a 100644
--- a/src/include/lwip/priv/tcp_priv.h
+++ b/src/include/lwip/priv/tcp_priv.h
@@ -452,7 +452,7 @@ void tcp_rst(u32_t seqno, u32_t ackno,
        const ip_addr_t *local_ip, const ip_addr_t *remote_ip,
        u16_t local_port, u16_t remote_port);
 
-u32_t tcp_next_iss(void);
+u32_t tcp_next_iss(struct tcp_pcb *pcb);
 
 err_t tcp_keepalive(struct tcp_pcb *pcb);
 err_t tcp_zero_window_probe(struct tcp_pcb *pcb);