diff --git a/Data/Sys/GameSettings/GSX.ini b/Data/Sys/GameSettings/GSX.ini
index beba2cda9e..d64006e60e 100644
--- a/Data/Sys/GameSettings/GSX.ini
+++ b/Data/Sys/GameSettings/GSX.ini
@@ -3,16 +3,9 @@
 [Core]
 # Values set here will override the main Dolphin settings.
 MMU = 1
-# LLE audio enabled by default for a listenable output
-DSPHLE = False
-
-[DSP]
-# Ensure the LLE recompiler gets selected and not interpreter.
-EnableJIT = True 
 
 [EmuState]
 # The Emulation State. 1 is worst, 5 is best, 0 is not set.
-EmulationIssues = Needs LLE audio for proper sound.
 EmulationStateId = 4
 
 [OnLoad]
diff --git a/Source/Core/Core/HW/DSP.cpp b/Source/Core/Core/HW/DSP.cpp
index aae25d8298..4795eb6b87 100644
--- a/Source/Core/Core/HW/DSP.cpp
+++ b/Source/Core/Core/HW/DSP.cpp
@@ -408,15 +408,14 @@ static void GenerateDSPInterrupt(u64 DSPIntType, s64 cyclesLate)
   // DSP_CONTROL - we mask by (INT_DSP | INT_ARAM | INT_AID) just to ensure people
   // don't call this with bogus values.
   s_dspState.Hex |= (DSPIntType & (INT_DSP | INT_ARAM | INT_AID));
-
   UpdateInterrupts();
 }
 
 // CALLED FROM DSP EMULATOR, POSSIBLY THREADED
-void GenerateDSPInterruptFromDSPEmu(DSPInterruptType type)
+void GenerateDSPInterruptFromDSPEmu(DSPInterruptType type, int cycles_into_future)
 {
-  // TODO: Maybe rethink this? The timing is unpredictable.
-  CoreTiming::ScheduleEvent(0, s_et_GenerateDSPInterrupt, type, CoreTiming::FromThread::ANY);
+  CoreTiming::ScheduleEvent(cycles_into_future, s_et_GenerateDSPInterrupt, type,
+                            CoreTiming::FromThread::ANY);
 }
 
 // called whenever SystemTimers thinks the DSP deserves a few more cycles
diff --git a/Source/Core/Core/HW/DSP.h b/Source/Core/Core/HW/DSP.h
index 05bbffa86a..2447685a2e 100644
--- a/Source/Core/Core/HW/DSP.h
+++ b/Source/Core/Core/HW/DSP.h
@@ -69,7 +69,8 @@ DSPEmulator* GetDSPEmulator();
 
 void DoState(PointerWrap& p);
 
-void GenerateDSPInterruptFromDSPEmu(DSPInterruptType type);
+// TODO: Maybe rethink this? The timing is unpredictable.
+void GenerateDSPInterruptFromDSPEmu(DSPInterruptType type, int cycles_into_future = 0);
 
 // Audio/DSP Helper
 u8 ReadARAM(u32 address);
diff --git a/Source/Core/Core/HW/DSPHLE/MailHandler.cpp b/Source/Core/Core/HW/DSPHLE/MailHandler.cpp
index fc5cb8bf87..da1ccfd29b 100644
--- a/Source/Core/Core/HW/DSPHLE/MailHandler.cpp
+++ b/Source/Core/Core/HW/DSPHLE/MailHandler.cpp
@@ -22,21 +22,21 @@ CMailHandler::~CMailHandler()
   Clear();
 }
 
-void CMailHandler::PushMail(u32 _Mail, bool interrupt)
+void CMailHandler::PushMail(u32 mail, bool interrupt, int cycles_into_future)
 {
   if (interrupt)
   {
     if (m_Mails.empty())
     {
-      DSP::GenerateDSPInterruptFromDSPEmu(DSP::INT_DSP);
+      DSP::GenerateDSPInterruptFromDSPEmu(DSP::INT_DSP, cycles_into_future);
     }
     else
     {
       m_Mails.front().second = true;
     }
   }
-  m_Mails.emplace(_Mail, false);
-  DEBUG_LOG(DSP_MAIL, "DSP writes 0x%08x", _Mail);
+  m_Mails.emplace(mail, false);
+  DEBUG_LOG(DSP_MAIL, "DSP writes 0x%08x", mail);
 }
 
 u16 CMailHandler::ReadDSPMailboxHigh()
diff --git a/Source/Core/Core/HW/DSPHLE/MailHandler.h b/Source/Core/Core/HW/DSPHLE/MailHandler.h
index d02ec9ffbe..a3503cefb7 100644
--- a/Source/Core/Core/HW/DSPHLE/MailHandler.h
+++ b/Source/Core/Core/HW/DSPHLE/MailHandler.h
@@ -21,7 +21,8 @@ public:
   CMailHandler();
   ~CMailHandler();
 
-  void PushMail(u32 _Mail, bool interrupt = false);
+  // TODO: figure out correct timing for interrupts rather than defaulting to "immediately."
+  void PushMail(u32 mail, bool interrupt = false, int cycles_into_future = 0);
   void Clear();
   void Halt(bool _Halt);
   void DoState(PointerWrap& p);
diff --git a/Source/Core/Core/HW/DSPHLE/UCodes/AX.cpp b/Source/Core/Core/HW/DSPHLE/UCodes/AX.cpp
index 7c9e745fd1..8cf4c33507 100644
--- a/Source/Core/Core/HW/DSPHLE/UCodes/AX.cpp
+++ b/Source/Core/Core/HW/DSPHLE/UCodes/AX.cpp
@@ -77,7 +77,22 @@ void AXUCode::LoadResamplingCoefficients()
 void AXUCode::SignalWorkEnd()
 {
   // Signal end of processing
-  m_mail_handler.PushMail(DSP_YIELD, true);
+  // TODO: figure out how many cycles this is actually supposed to take
+
+  // The Clone Wars hangs upon initial boot if this interrupt happens too quickly after submitting a
+  // command list. When played in DSP-LLE, the interrupt lags by about 160,000 cycles, though any
+  // value greater than or equal to 814 will work here. In other games, the lag can be as small as
+  // 50,000 cycles (in Metroid Prime) and as large as 718,092 cycles (in Tales of Symphonia!).
+
+  // On the PowerPC side, hthh_ discovered that The Clone Wars tracks a "AXCommandListCycles"
+  // variable which matches the aforementioned 160,000 cycles. It's initialized to ~2500 cycles for
+  // a minimal, empty command list, so that should be a safe number for pretty much anything a game
+  // does.
+
+  // For more information, see https://bugs.dolphin-emu.org/issues/10265.
+  constexpr int AX_EMPTY_COMMAND_LIST_CYCLES = 2500;
+
+  m_mail_handler.PushMail(DSP_YIELD, true, AX_EMPTY_COMMAND_LIST_CYCLES);
 }
 
 void AXUCode::HandleCommandList()